Proteins: Difference between revisions
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'''Proteins''' are a particular group of [[Linear polymers |linear chain]] [[polymers]], built up from a collection of 20 different monomers known as '''amino acids'''. Proteins, unlike many synthetic polymers, have a very specific sequence (and hence length), which results in a specific three-dimensional structure. Presently much computational effort is dedicated to the prediction of such structure from a given sequence. | |||
==Potentials and models== | ==Potentials and models== | ||
*[[CABS model]] | |||
*[[Chen and Imamura model]] | |||
*[[DFIRE model]] | |||
*[[Go potential]] | *[[Go potential]] | ||
*[[Irbäck hydrogen bond model]] | *[[Irbäck hydrogen bond model]] | ||
*[[Nanias model]] | *[[Nanias model]] | ||
*[[Patchy particles]] | |||
*[[TE-13 model]] | *[[TE-13 model]] | ||
==Systems== | ==Systems== | ||
*[[Amelogenin]] | |||
*[[Chymotrypsin Inhibitor 2 (CI2)]] | |||
*[[Ubiquitin]] | *[[Ubiquitin]] | ||
*[[Villin headpiece]] | *[[Villin headpiece]] | ||
*[[Bovine pancreatic trypsin inhibitor (BPTI)]] | |||
==Other== | ==Other== | ||
*[[Folding@Home]] | *[[Folding@Home]] | ||
*[[I-TASSER]] | |||
==General Reading== | ==General Reading== | ||
*[http://dx.doi.org/10.1126/science.181.4096.223 Christian B. Anfinsen "Principles that Govern the Folding of Protein Chains", Science '''181''' pp. 223-230 (1973)] | |||
* Thomas E. Creighton "Proteins: Structures and Molecular Properties", W. H. Freeman, Second Edition edition (1993) ISBN 071677030X | |||
*[http://dx.doi.org/10.1140/epjd/e2006-00241-9 A.V. Yakubovich, I.A. Solov'yov, A.V. Solov'yov and W. Greiner "Phase transition in polypeptides: a step towards the understanding of protein folding", The European Physical Journal D '''40''' pp. 363-367 (2006)] | |||
*[http://dx.doi.org/10.1063/1.3626859 Arieh Ben-Naim "Some aspects of the protein folding problem examined in one-dimensional systems", Journal of Chemical Physics '''135''' 085104 (2011)] | |||
* Arieh Ben-Naim "The Protein Folding Problem and Its Solutions", World Scientific Publishing (2013) ISBN 978-981-4436-35-9 | |||
* Arieh Ben-Naim "Myths and Verities in Protein Folding Theories", World Scientific Publishing (2016) ISBN 978-981-4725-98-9 | |||
[[category: proteins]] | |||
Latest revision as of 11:44, 16 September 2016
Proteins are a particular group of linear chain polymers, built up from a collection of 20 different monomers known as amino acids. Proteins, unlike many synthetic polymers, have a very specific sequence (and hence length), which results in a specific three-dimensional structure. Presently much computational effort is dedicated to the prediction of such structure from a given sequence.
Potentials and models[edit]
- CABS model
- Chen and Imamura model
- DFIRE model
- Go potential
- Irbäck hydrogen bond model
- Nanias model
- Patchy particles
- TE-13 model
Systems[edit]
- Amelogenin
- Chymotrypsin Inhibitor 2 (CI2)
- Ubiquitin
- Villin headpiece
- Bovine pancreatic trypsin inhibitor (BPTI)
Other[edit]
General Reading[edit]
- Christian B. Anfinsen "Principles that Govern the Folding of Protein Chains", Science 181 pp. 223-230 (1973)
- Thomas E. Creighton "Proteins: Structures and Molecular Properties", W. H. Freeman, Second Edition edition (1993) ISBN 071677030X
- A.V. Yakubovich, I.A. Solov'yov, A.V. Solov'yov and W. Greiner "Phase transition in polypeptides: a step towards the understanding of protein folding", The European Physical Journal D 40 pp. 363-367 (2006)
- Arieh Ben-Naim "Some aspects of the protein folding problem examined in one-dimensional systems", Journal of Chemical Physics 135 085104 (2011)
- Arieh Ben-Naim "The Protein Folding Problem and Its Solutions", World Scientific Publishing (2013) ISBN 978-981-4436-35-9
- Arieh Ben-Naim "Myths and Verities in Protein Folding Theories", World Scientific Publishing (2016) ISBN 978-981-4725-98-9